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Volume 3, Issue 4

Effects of hydroxychloroquine on intestinal mucosal barrier and gut microbiota in inflammatory-bowel disease of mice

www.doi.org/10.52768/jjgastro/1142

Hydroxychloroquine (HCQ) effect on gut microbiota and intestinal mucosal barrier in Inflammatory-Bowel Disease (IBD) was evaluated in this work. Here, we established an IBD model before treating mice with HCQ. After HCQ treatment, the body weight, colon length and fecal occult blood of mice did not change significantly.

Use of accessory devices in the endoscopic removal of esophageal foreign bodies

www.doi.org/10.52768/jjgastro/1143

Background/Aims: The accessory devices used for esophageal foreign body removal have not been thoroughly investigated. This study investigated the appropriate use of endoscopic accessory devices for removing esophageal foreign bodies.

Ectopic duodenal mucosa with adenomatous hyperplasia in the stomach: A case report

www.doi.org/10.52768/jjgastro/1144

A 49-year-old man presented with abdominal distension and loss of appetite for 1 month as the main symptoms. Gastroscopy revealed a space occupying lesion in the pylorus of gastric antrum. After electroresection, pathological and immunohistochemical examination showed that it was "ectopic duodenal mucosa with adenomatous hyperplasia in the stomach".

Study of insulin-like growth factors and their association with clinic pathological features and survival in colon cancer

www.doi.org/10.52768/jjgastro/1145

The present study aimed to elucidate the clinicopathological relationship of insulin-like growth factor signaling pathway in patients with advanced colon adenocarcinoma. The relationship of protein expression in this pathway is controversial when associated with the disease prognosis, including its relationship with type II diabetes mellitus.

The feasibility of sequential short-course radiation therapy and chemotherapy in the neoadjuvant treatment of rectal adenocarcinoma: Cases series treated in a Brazilian public health service

www.doi.org/10.52768/jjgastro/1146

Introduction: Total Neoadjuvant Therapy (TNT) is now recognized as the preferred standard for the treatment of locally advanced rectal cancer. With recent progress in surgery, radiotherapy and chemotherapy, management strategies have become more complex but also more refined, in order to adapt to each situation. Short-course radiotherapy can be an excellent alternative to reduce radiotherapy waiting lists in public institutions, with the possibility of good oncological results and good cost-effectiveness.