Sexually Transmitted Infections (STIs) can often mimic Inflammatory Bowel Disease (IBD) and should always be considered in the differential diagnosis of patients presenting with rectal manifestations. Unfortunately, the symptoms of lower gastrointestinal syphilis are often nonspecific or even absent, making the diagnosis particularly challenging.
There are four histologically defined esophageal mechanoreceptive agents with evidence-based functions, three are mechanoreceptors and one is a mechanoreceptive inhibitory afferent nerve. The slowly-adapting tension sensitive receptors of the esophageal myenteric plexus function.
Proton Pump Inhibitors (PPI) are widely prescribed for managing acid-related gastrointestinal disorders, such as Gastroesophageal Reflux Disease (GERD). While effective, long-term PPI use has been associated with the development of Fundic Gland Polyps (FGPs), benign gastric lesions with significant clinical implications.