www.doi.org/10.52768/jjgastro/1109
Gastric Cancer (GC) is highly prevalent in China, where its mortality rate accounts for 50% of global GC deaths. Currently, GC pathogenesis is not fully understood. In this study, three gene expression profile datasets were retrieved from Gene Expression Omnibus (GEO) and examined to identify core GC biomarkers. First, DEGs in datasets GSE54129, GSE13911, and GSE118916 were identified using NCBI GEO2R and Venn diagram analyses.
www.doi.org/10.52768/jjgastro/1110
Peritoneal metastasis of gastric cancer is common and the prognosis is generally poor. This retrospective study investigated whether peritoneal lavage cytology (CY) results may be predictive of peritoneal metastasis, and the potential risk factors for tumor outcomes. Seventy-four patients with primary gastric cancer (cT ≥ 2) between February 2015 and November 2018 were included.
www.doi.org/10.52768/jjgastro/1111
Midgut volvulus is a life-threatening condition that can lead to bowel ischemia and devastating results with high mortality incidence. An ovarian cyst can be accidentally discovered antenatal or postnatal and can be asymptomatic, mass presentation, or complicated presentation as torsion. The association of midgut volvulus and an ovarian cyst is exceptional.
www.doi.org/10.52768/jjgastro/1112
There has been a great deal of research going on in the subject of gut microbiome. The human gut microbiome harbors more than 100 trillion of different kinds of microbes which are essential for the normal functioning of the day-to-day metabolism and physiological functions. The disruption in the population and balance of gut microbiome can lead to various types of gastrointestinal conditions.
www.doi.org/10.52768/jjgastro/1113
Coeliac Disease (CD) is a common, chronic inflammatory disorder of the small bowel triggered by exposure to dietary gluten. Much is known about the pathogenesis of CD, with strong evidence implicating immune reactivity to both gliadin-related peptides and autoantigens. The natural history of CD is not well understood however-and so there remains uncertainty about whether it is an acquired condition, and if so, whether this acquisition is for life.